Comparing OncoCyte (NASDAQ:OCX) and Oruka Therapeutics (NASDAQ:ORKA)

Oruka Therapeutics (NASDAQ:ORKA) and OncoCyte (NASDAQ:OCX) are both small-cap medical companies, but which is the better investment? We will compare the two businesses based on the strength of their earnings, risk, valuation, dividends, analyst recommendations, institutional ownership and profitability.

Profitability

This table compares Oruka Therapeutics and OncoCyte’s net margins, return on equity and return on assets.

	Net Margins	Return on Equity	Return on Assets
Oruka Therapeutics	N/A	-20.18%	-19.51%
OncoCyte	-3,558.46%	-149.88%	-45.79%

Analyst Ratings

This is a breakdown of current ratings and recommmendations for Oruka Therapeutics and OncoCyte, as reported by MarketBeat.com.

	Sell Ratings	Hold Ratings	Buy Ratings	Strong Buy Ratings	Rating Score
Oruka Therapeutics	0	0	6	2	3.25
OncoCyte	0	2	2	0	2.50

Oruka Therapeutics currently has a consensus price target of $43.17, suggesting a potential upside of 61.79%. OncoCyte has a consensus price target of $4.06, suggesting a potential upside of 42.05%. Given Oruka Therapeutics’ stronger consensus rating and higher probable upside, equities research analysts clearly believe Oruka Therapeutics is more favorable than OncoCyte.

Insider and Institutional Ownership

56.4% of Oruka Therapeutics shares are owned by institutional investors. Comparatively, 55.4% of OncoCyte shares are owned by institutional investors. 22.7% of Oruka Therapeutics shares are owned by insiders. Comparatively, 1.6% of OncoCyte shares are owned by insiders. Strong institutional ownership is an indication that endowments, hedge funds and large money managers believe a company is poised for long-term growth.

Valuation & Earnings

This table compares Oruka Therapeutics and OncoCyte”s top-line revenue, earnings per share (EPS) and valuation.

	Gross Revenue	Price/Sales Ratio	Net Income	Earnings Per Share	Price/Earnings Ratio
Oruka Therapeutics	N/A	N/A	-$5.34 million	($6.00)	-4.44
OncoCyte	$1.50 million	32.09	-$27.78 million	N/A	N/A

Oruka Therapeutics has higher earnings, but lower revenue than OncoCyte.

Risk and Volatility

Oruka Therapeutics has a beta of 0.87, suggesting that its stock price is 13% less volatile than the S&P 500. Comparatively, OncoCyte has a beta of 1, suggesting that its stock price has a similar volatility profile to the S&P 500.

Summary

Oruka Therapeutics beats OncoCyte on 10 of the 12 factors compared between the two stocks.

About Oruka Therapeutics

ARCA biopharma, Inc., a biopharmaceutical company, develops genetically-targeted therapies for heart failure and cardiovascular diseases. It is positioned to bring personalized therapies for the treatment of cardiovascular disease, through the use of genetics. Complementing the Company’s cardiovascular science, ARCA’s management team has significant experience in developing and commercializing cardiovascular products. The Company’s business focus combines expertise in cardiovascular pathophysiology, molecular genetics, clinical development and product commercialization. It is currently developing Gencaro (bucindolol hydrochloride), a cardiovascular drug for the treatment of chronic heart failure. The company is based in Broomfield, Colorado.

About OncoCyte

OncoCyte Corporation, a precision diagnostics company, focuses on development and commercialization of proprietary tests in the United States and internationally. The company is developing DetermaIO, a gene expression test that assesses the tumor microenvironment to predict response to immunotherapies; DetermaCNI, a blood-based monitoring tool for monitoring therapeutic efficacy in cancer patients; and VitaGraft, a blood-based solid organ transplantation monitoring test. It also provides testing services for biomarker discovery, assay design and development, clinical trial support, and various biomarker tests. The company has a collaboration agreement with Bio-Rad Laboratories, Inc. (Bio-Rad) to collaborate in the development and the commercialization of research use only and in vitro diagnostics kitted transplant products using Bio-Rad's ddPCR instruments and reagents. OncoCyte Corporation was incorporated in 2009 and is based in Irvine, California.